{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10472664","patent":{"patent_number":"US-10472664","title":"Screening assay for identification of poly(ADP-ribose) polymerase 1 inhibitors","assignee":null,"inventors":[],"filing_date":"2015-09-30T00:00:00.000Z","publication_date":"2019-11-12T00:00:00.000Z","cpc_codes":["C12Q","G01N","G01N","G01N","G01N","G01N"],"num_claims":10,"abstract":"Screening methods as well as systems and kits for identifying inhibitors of DNA-independent, histone H4-dependent activation of PARP-1 are provided. The methods comprise screening molecules for their capacity to inhibit the activation and/or biologic activity of PARP-1, as measured by poly(ADP)-ribose production from nicotinamide adenine dinucleotide. PARP-1 inhibitors identified through the screening methods may be used to treat cancer in which PARP-1 activation or biologic activity plays a role."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Screening assay for identification of poly(ADP-ribose) polymerase 1 inhibitors","description":"Screening methods as well as systems and kits for identifying inhibitors of DNA-independent, histone H4-dependent activation of PARP-1 are provided. The methods comprise screening molecules for their ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10472664","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10472664","citation_suggestion":"Patentable. \"Screening assay for identification of poly(ADP-ribose) polymerase 1 inhibitors\" (US-10472664). https://patentable.app/patents/US-10472664","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10472664","json":"https://patentable.app/api/llm-context/US-10472664","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T03:13:13.547Z"}