{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10488321","patent":{"patent_number":"US-10488321","title":"Devices and methods for high-throughput single cell and biomolecule analysis and retrieval in a microfluidic chip","assignee":null,"inventors":[],"filing_date":"2016-03-18T00:00:00.000Z","publication_date":"2019-11-26T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N","G01N","G01N","G01N","G01N","G01N"],"num_claims":12,"abstract":"Described here is a device comprising a microfluidic chip and an acoustic transducer external to the microfluidic chip, wherein the microfluidic chip comprises a channel in communication with a microwell having a volume less than one microliter, and wherein the acoustic transducer is coupled to the microfluidic chip via a coupling medium. Also described here is a method for analyzing a cell or a biomolecule, comprising applying a focused acoustic beam to a microfluidic chip comprising a channel in fluid communication with a microwell having a volume less than one microliter, wherein the microwell comprises an aqueous compartment comprising a cell or a biomolecule, wherein the channel comprises a non-aqueous liquid phase immiscible with the aqueous compartment which encapsulates the aqueous compartment in the microwell, and wherein the acoustic beam displaces a meniscus at an interface of the aqueous compartment and the non-aqueous liquid phase thereby ejecting the aqueous compartment from the microwell into the channel as an aqueous droplet."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Devices and methods for high-throughput single cell and biomolecule analysis and retrieval in a microfluidic chip","description":"Described here is a device comprising a microfluidic chip and an acoustic transducer external to the microfluidic chip, wherein the microfluidic chip comprises a channel in communication with a microw","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10488321","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10488321","citation_suggestion":"Patentable. \"Devices and methods for high-throughput single cell and biomolecule analysis and retrieval in a microfluidic chip\" (US-10488321). https://patentable.app/patents/US-10488321","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10488321","json":"https://patentable.app/api/llm-context/US-10488321","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T06:52:04.955Z"}