{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10488421","patent":{"patent_number":"US-10488421","title":"Methods for reducing the risk of osteoarthritis of the knee","assignee":null,"inventors":[],"filing_date":"2018-08-03T00:00:00.000Z","publication_date":"2019-11-26T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N","G01N","G01N"],"num_claims":12,"abstract":"Methods for reducing the risk of osteoarthritis of the knee in a human determined to have an elevated risk of osteoarthritis of the knee are provided. The methods involve administering an intervention, such as physical therapy, to a human that has an increased expression level of biomarker C1,2C, C2C, or CPII compared to a normal control, or a decreased expression level of biomarker CS846 compared to a normal control, or a combination thereof."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Methods for reducing the risk of osteoarthritis of the knee","description":"Methods for reducing the risk of osteoarthritis of the knee in a human determined to have an elevated risk of osteoarthritis of the knee are provided. The methods involve administering an intervention","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10488421","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10488421","citation_suggestion":"Patentable. \"Methods for reducing the risk of osteoarthritis of the knee\" (US-10488421). https://patentable.app/patents/US-10488421","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10488421","json":"https://patentable.app/api/llm-context/US-10488421","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T08:00:07.070Z"}