{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10492723","patent":{"patent_number":"US-10492723","title":"Predicting immunotherapy response in non-small cell lung cancer patients with quantitative vessel tortuosity","assignee":null,"inventors":[],"filing_date":"2018-01-30T00:00:00.000Z","publication_date":"2019-12-03T00:00:00.000Z","cpc_codes":["G16H","A61B","A61B","A61B","A61B","A61B","A61B","G06F","G06F","G06T","G06T","G06T","G16H","G16H","G16H","G16H","A61B","A61B","A61B","G06T","G06T","G06T","G06T","G06T","G06V","G06V","G06V"],"num_claims":20,"abstract":"Embodiments classify a region of tissue demonstrating non-small cell lung cancer using quantified vessel tortuosity (QVT). One example apparatus includes annotation circuitry configured to segment a lung region from surrounding anatomy in the region of tissue represented in a radiological image and segment a nodule from the lung region by defining a nodule boundary; vascular segmentation circuitry configured to generate a three dimensional (3D) segmented vasculature by segmenting a vessel associated with the nodule, and to identify a center line of the 3D segmented vasculature; QVT feature extraction circuitry configured to extract a set of QVT features from the radiological image; and classification circuitry configured to compute a probability that the region of tissue will respond to immunotherapy and generate a classification that the region of tissue is a responder or a non-responder based, at least in part, on the probability."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Predicting immunotherapy response in non-small cell lung cancer patients with quantitative vessel tortuosity","description":"Embodiments classify a region of tissue demonstrating non-small cell lung cancer using quantified vessel tortuosity (QVT). One example apparatus includes annotation circuitry configured to segment a l","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10492723","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10492723","citation_suggestion":"Patentable. \"Predicting immunotherapy response in non-small cell lung cancer patients with quantitative vessel tortuosity\" (US-10492723). https://patentable.app/patents/US-10492723","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10492723","json":"https://patentable.app/api/llm-context/US-10492723","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T12:00:44.879Z"}