{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10503959","patent":{"patent_number":"US-10503959","title":"Predicting cancer progression using cell run length features","assignee":null,"inventors":[],"filing_date":"2018-02-21T00:00:00.000Z","publication_date":"2019-12-10T00:00:00.000Z","cpc_codes":["G06V","G06T","G06T","G06V","G06T","G06T","G06T","G06T","G06T","G06T","G06T","G06T","G06T"],"num_claims":20,"abstract":"Embodiments include an image acquisition circuit configured to access an image of a region of tissue demonstrating cancerous pathology, a nuclei detection and graphing circuit configured to detect cellular nuclei represented in the image; and construct a nuclear sub-graph based on the detected cellular nuclei, where a node of the sub-graph is a nuclear centroid of a cellular nucleus; a cell run length (CRF) circuit configured to compute a CRF vector based on the sub-graph; compute a set of CRF features based on the CRF vector and the sub-graph; and generate a CRF signature based, at least in part, on the set of CRF features; and a classification circuit configured to compute a probability that the region of tissue will experience cancer progression, based, at least in part, on the CRF signature; and generate a classification of the region of tissue as a progressor or non-progressor."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Predicting cancer progression using cell run length features","description":"Embodiments include an image acquisition circuit configured to access an image of a region of tissue demonstrating cancerous pathology, a nuclei detection and graphing circuit configured to detect cel","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10503959","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10503959","citation_suggestion":"Patentable. \"Predicting cancer progression using cell run length features\" (US-10503959). https://patentable.app/patents/US-10503959","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10503959","json":"https://patentable.app/api/llm-context/US-10503959","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T14:46:01.765Z"}