{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10508301","patent":{"patent_number":"US-10508301","title":"Detection of 5-hydroxymethylcytosine by glycosylation","assignee":null,"inventors":[],"filing_date":"2018-06-19T00:00:00.000Z","publication_date":"2019-12-17T00:00:00.000Z","cpc_codes":["C12Q","C12Q","C12Q","C12Q","G01N","G01N","C12Q","C12Q","C12Q","C12Q","G01N"],"num_claims":12,"abstract":"The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Detection of 5-hydroxymethylcytosine by glycosylation","description":"The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic act","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10508301","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10508301","citation_suggestion":"Patentable. \"Detection of 5-hydroxymethylcytosine by glycosylation\" (US-10508301). https://patentable.app/patents/US-10508301","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10508301","json":"https://patentable.app/api/llm-context/US-10508301","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T20:04:57.213Z"}