{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10526654","patent":{"patent_number":"US-10526654","title":"Simple detection method for RNA modification, and method for detecting type-II diabetes using said detection method","assignee":null,"inventors":[],"filing_date":"2014-03-06T00:00:00.000Z","publication_date":"2020-01-07T00:00:00.000Z","cpc_codes":["C12Q","G16B","G16B","C12Q","C12Q","C12Q","C12Q"],"num_claims":20,"abstract":"An object of the present invention is to provide a method for detecting a modification present in RNA using a small amount of RNA sample. Another object of the present invention is to provide a method for detecting a modification present in tRNA, for example, thiomethylation. Still another object of the present invention is to provide a method for detecting the thiomethylation of tRNA, thereby diagnosing human type 2 diabetes or the risk thereof. The present invention is characterized in that, with respect to a modification present in RNA in an RNA sample, cDNA is produced by reverse transcription of RNA using a first primer, and the resulting amount of cDNA is compared with the amount of cDNA produced by reverse transcription of RNA using a second primer, thereby detecting a modification (e.g., thiomethylation) present in RNA."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Simple detection method for RNA modification, and method for detecting type-II diabetes using said detection method","description":"An object of the present invention is to provide a method for detecting a modification present in RNA using a small amount of RNA sample. Another object of the present invention is to provide a method","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10526654","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10526654","citation_suggestion":"Patentable. \"Simple detection method for RNA modification, and method for detecting type-II diabetes using said detection method\" (US-10526654). https://patentable.app/patents/US-10526654","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10526654","json":"https://patentable.app/api/llm-context/US-10526654","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T11:18:03.220Z"}