{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-10545090","patent":{"patent_number":"US-10545090","title":"Method and system for more reliable determination of interaction parameters for low affinity analytes","assignee":null,"inventors":[],"filing_date":"2010-11-29T00:00:00.000Z","publication_date":"2020-01-28T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N","G01N"],"num_claims":8,"abstract":"A method of determining one or more interaction parameters for the interaction between an analyte and a ligand using a biosensor, which comprises the steps of: A: providing a sensor surface having the ligand immobilized thereto, B: contacting the sensor surface with a control analyte, C: registering the sensor response from binding of the control analyte to binding sites of the ligand, D: determining the control saturation response (RmaxC) for the interaction between the control analyte and the ligand, E: transforming the control saturation response (RmaxC) to an analyte saturation response (RmaxA) using the relative molar response contribution of the analyte and the control analyte. F: contacting the sensor surface with one or more samples containing different concentrations of the analyte, G: registering the sensor response from binding of the analyte to the binding sites, and H: fitting the registered sensor response to a predetermined interaction model using the analyte saturation response (RmaxA) to determine the interaction parameters."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method and system for more reliable determination of interaction parameters for low affinity analytes","description":"A method of determining one or more interaction parameters for the interaction between an analyte and a ligand using a biosensor, which comprises the steps of: A: providing a sensor surface having the","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-10545090","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-10545090","citation_suggestion":"Patentable. \"Method and system for more reliable determination of interaction parameters for low affinity analytes\" (US-10545090). https://patentable.app/patents/US-10545090","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-10545090","json":"https://patentable.app/api/llm-context/US-10545090","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T13:43:06.556Z"}