{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11250566","patent":{"patent_number":"US-11250566","title":"Methods and systems for evaluation of immune cell infiltrate in tumor samples","assignee":null,"inventors":[],"filing_date":"2020-01-24T00:00:00.000Z","publication_date":"2022-02-15T00:00:00.000Z","cpc_codes":["G06T","C12Q","G01N","G01N","C12Q","G06T","G06T","G06T","G06T","G06T","G16H"],"num_claims":35,"abstract":"Immune context scores are calculated for tumor tissue samples using continuous scoring functions. Feature metrics for at least one immune cell marker are calculated for a region or regions of interest, the feature metrics including at least a quantitative measure of human CD3 or total lymphocyte counts. A continuous scoring function is then applied to a feature vector including the feature metric and at least one additional metric related to an immunological biomarker, the output of which is an immune context score. The immune context score may then be plotted as a function of a diagnostic or treatment metric, such as a prognostic metric (e.g. overall survival, disease-specific survival, progression-free survival) or a predictive metric (e.g. likelihood of response to a particular treatment course). The immune context score may then be incorporated into diagnostic and/or treatment decisions."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Methods and systems for evaluation of immune cell infiltrate in tumor samples","description":"Immune context scores are calculated for tumor tissue samples using continuous scoring functions. Feature metrics for at least one immune cell marker are calculated for a region or regions of interest","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11250566","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11250566","citation_suggestion":"Patentable. \"Methods and systems for evaluation of immune cell infiltrate in tumor samples\" (US-11250566). https://patentable.app/patents/US-11250566","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11250566","json":"https://patentable.app/api/llm-context/US-11250566","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T09:22:27.206Z"}