{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11253590","patent":{"patent_number":"US-11253590","title":"Antibodies specific to glycosylated BTLA (B- and T- lymphocyte attenuator)","assignee":null,"inventors":[],"filing_date":"2016-12-01T00:00:00.000Z","publication_date":"2022-02-22T00:00:00.000Z","cpc_codes":["G01N"],"num_claims":30,"abstract":"Provided herein are molecules, such as antibodies, that selectively bind to glycosylated BTLA (B- and T-lymphocyte attenuator) relative to unglycosylated BTLA. Methods for making and using such molecules are also provided, including methods for treating or diagnosing cancer. In some embodiments, the anti-glycosylated BTLA antibodies provided herein can immunospecifically bind to glycosylated wild-type BTLA (WT). In some embodiments, the anti-glycosylated BTLA antibodies provided herein can immunospecifically bind to one or more BTLA double mutants that retain only a single glycosylation site at BTLA N75, N94 or N110. In some embodiments, the anti-glycosylated BTLA antibodies provided herein show only background binding, if any, to a BTLA triple mutant, that retains none of BTLA's N75, N94, or N110 0-glycosylation sites."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Antibodies specific to glycosylated BTLA (B- and T- lymphocyte attenuator)","description":"Provided herein are molecules, such as antibodies, that selectively bind to glycosylated BTLA (B- and T-lymphocyte attenuator) relative to unglycosylated BTLA. Methods for making and using such molecu","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11253590","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11253590","citation_suggestion":"Patentable. \"Antibodies specific to glycosylated BTLA (B- and T- lymphocyte attenuator)\" (US-11253590). https://patentable.app/patents/US-11253590","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11253590","json":"https://patentable.app/api/llm-context/US-11253590","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T22:15:26.690Z"}