{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11254986","patent":{"patent_number":"US-11254986","title":"Gene signature for immune therapies in cancer","assignee":null,"inventors":[],"filing_date":"2016-07-21T00:00:00.000Z","publication_date":"2022-02-22T00:00:00.000Z","cpc_codes":["C12Q","G16H","C12Q","C12Q"],"num_claims":17,"abstract":"An immune response subtype of cancer is associated with DNA damage which allows subjects to be stratified for particular therapies including immune therapies which may be combined with DNA damage therapeutics. A method for predicting responsiveness to an antagonist of an inhibitory immune checkpoint and/or an agonist of a stimulatory immune checkpoint comprises determining the expression level of at least one gene selected from Table 2B, 2A or 1 in a sample from the subject. The determined expression level is used to predict responsiveness to an antagonist of an inhibitory immune checkpoint and/or an agonist of a stimulatory immune checkpoint."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Gene signature for immune therapies in cancer","description":"An immune response subtype of cancer is associated with DNA damage which allows subjects to be stratified for particular therapies including immune therapies which may be combined with DNA damage ther","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11254986","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11254986","citation_suggestion":"Patentable. \"Gene signature for immune therapies in cancer\" (US-11254986). https://patentable.app/patents/US-11254986","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11254986","json":"https://patentable.app/api/llm-context/US-11254986","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T16:57:17.624Z"}