{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11262306","patent":{"patent_number":"US-11262306","title":"Method to keep the excitation light sheet in focus in selective plane illumination microscopy","assignee":null,"inventors":[],"filing_date":"2018-05-04T00:00:00.000Z","publication_date":"2022-03-01T00:00:00.000Z","cpc_codes":["G01N"],"num_claims":20,"abstract":"Keeping the excitation light sheet in focus is critical in selective plane illumination microscopy (SPIM) to ensure its 3D imaging ability. Unfortunately, an effective method that can be used in SPIM on general biological specimens to find the axial position of the excitation light sheet and keep it in focus is barely available. Here, we present a method to solve the problem. We investigate its mechanism and demonstrate its performance on a lattice light sheet microscope."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method to keep the excitation light sheet in focus in selective plane illumination microscopy","description":"Keeping the excitation light sheet in focus is critical in selective plane illumination microscopy (SPIM) to ensure its 3D imaging ability. Unfortunately, an effective method that can be used in SPIM ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11262306","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11262306","citation_suggestion":"Patentable. \"Method to keep the excitation light sheet in focus in selective plane illumination microscopy\" (US-11262306). https://patentable.app/patents/US-11262306","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11262306","json":"https://patentable.app/api/llm-context/US-11262306","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T14:59:36.985Z"}