{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11462296","patent":{"patent_number":"US-11462296","title":"Identifying presence and composition of cell-free nucleic acids","assignee":null,"inventors":[],"filing_date":"2017-10-13T00:00:00.000Z","publication_date":"2022-10-04T00:00:00.000Z","cpc_codes":["G16B","C12Q","G01N","G16B","G16B","G16B","G16B","G16B","C12Q"],"num_claims":30,"abstract":"This disclosure describes example techniques and systems for identifying the presence and/or composition of nucleic acids in the blood of a host organism of a model species harboring tissue of a donor organism of another species. For example, the technique may involve identifying the presence and composition of nucleic acids in the blood of a mouse harboring tissue of a human or another companion animal. These cell-free nucleic acids that are identified can be used as biomarkers to determine the presence of a disease, its biological behavior, its rate of progression, and/or the response of the disease to one or more unique therapies. In other examples, the cell-free nucleic acids may be used as biomarkers to determine a response of the host species to the tissue of the donor organism or a response of tissue derived from the second organism to transplantation within the first organism of the first species."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Identifying presence and composition of cell-free nucleic acids","description":"This disclosure describes example techniques and systems for identifying the presence and/or composition of nucleic acids in the blood of a host organism of a model species harboring tissue of a donor","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11462296","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11462296","citation_suggestion":"Patentable. \"Identifying presence and composition of cell-free nucleic acids\" (US-11462296). https://patentable.app/patents/US-11462296","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11462296","json":"https://patentable.app/api/llm-context/US-11462296","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T09:24:04.774Z"}