{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11471463","patent":{"patent_number":"US-11471463","title":"Enhancers of cellular cannibalism for use to sensitize tumors to radiation therapy","assignee":null,"inventors":[],"filing_date":"2018-01-23T00:00:00.000Z","publication_date":"2022-10-18T00:00:00.000Z","cpc_codes":["A61N","G01N","A61N","G01N"],"num_claims":15,"abstract":"The present invention is drawn to the use of the compounds highlighted in Tables 1 & 2 and analogs thereof, for enhancing IR-mediated cellular cannibalism in cancer cells. Said compounds are herein called “enhancers of IR-mediated cellular cannibalism”. They can be used to enhance tumor immunogenicity and/or to induce a significant protective anticancer immune response in subjects that will receive or that have received a radiotherapy treatment. In other words, said compounds can be used to potentiate a radiotherapy treatment in a subject in need thereof. Said compounds are preferably chosen in the group consisting of: Mebhydroline 1,5-napthalene disulfonate salt, Flurbiprofen, Minaprine dihydrochloride, Myricetin, Digoxin, Digitoxin, Lanatoside, LOPA87, VP331, RN-1-026, SG6163F, VP450, and VP43."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Enhancers of cellular cannibalism for use to sensitize tumors to radiation therapy","description":"The present invention is drawn to the use of the compounds highlighted in Tables 1 & 2 and analogs thereof, for enhancing IR-mediated cellular cannibalism in cancer cells. Said compounds are herein ca","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11471463","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11471463","citation_suggestion":"Patentable. \"Enhancers of cellular cannibalism for use to sensitize tumors to radiation therapy\" (US-11471463). https://patentable.app/patents/US-11471463","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11471463","json":"https://patentable.app/api/llm-context/US-11471463","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T00:36:46.337Z"}