{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11473137","patent":{"patent_number":"US-11473137","title":"Alignment free filtering for identifying fusions","assignee":null,"inventors":[],"filing_date":"2018-06-12T00:00:00.000Z","publication_date":"2022-10-18T00:00:00.000Z","cpc_codes":["C12Q","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16B","G16H","G16H","C12Q","C12Q","C12Q","C12Q","C12Q","C12Q","C12Q"],"num_claims":27,"abstract":"Cell free nucleic acids from a test sample obtained from an individual are analyzed to identify possible fusion events. Cell free nucleic acids are sequenced and processed to generate fragments. Fragments are decomposed into kmers and the kmers are either analyzed de novo or compared to targeted nucleic acid sequences that are known to be associated with fusion gene pairs of interest. Thus, kmers that may have originated from a fusion event can be identified. These kmers are consolidated to generate gene ranges from various genes that match sequences in the fragment. A candidate fusion event can be called given the spanning of one or more gene ranges across the fragment."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Alignment free filtering for identifying fusions","description":"Cell free nucleic acids from a test sample obtained from an individual are analyzed to identify possible fusion events. Cell free nucleic acids are sequenced and processed to generate fragments. Fragm","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11473137","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11473137","citation_suggestion":"Patentable. \"Alignment free filtering for identifying fusions\" (US-11473137). https://patentable.app/patents/US-11473137","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11473137","json":"https://patentable.app/api/llm-context/US-11473137","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T03:14:03.819Z"}