{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11488686","patent":{"patent_number":"US-11488686","title":"Method and system for in silico testing of actives on human skin","assignee":null,"inventors":[],"filing_date":"2018-02-20T00:00:00.000Z","publication_date":"2022-11-01T00:00:00.000Z","cpc_codes":["G16B","G16B","G16B","G16H","G16H"],"num_claims":19,"abstract":"A method and system for in-silico testing of actives on human skin is described. The present invention discloses a micro and macroscopic level model of the skins upper protective layer Stratum-Corneum. The invention presents a multi-scale modeling framework for the calculation of diffusion and release profile of different actives like drugs, particles and cosmetics through developed skin model using molecular dynamics simulations and computational fluid dynamics approach. The systems consist of a molecular model of the skin's upper layer stratum corneum and permeate molecules. The system also consists of a macroscopic transport model of stratum corneum. The transport model is used to generate the release profile of the active molecule."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method and system for in silico testing of actives on human skin","description":"A method and system for in-silico testing of actives on human skin is described. The present invention discloses a micro and macroscopic level model of the skins upper protective layer Stratum-Corneum","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11488686","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11488686","citation_suggestion":"Patentable. \"Method and system for in silico testing of actives on human skin\" (US-11488686). https://patentable.app/patents/US-11488686","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11488686","json":"https://patentable.app/api/llm-context/US-11488686","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T15:32:20.154Z"}