{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11493520","patent":{"patent_number":"US-11493520","title":"Assays for nucleosome remodeling activity","assignee":null,"inventors":[],"filing_date":"2018-05-18T00:00:00.000Z","publication_date":"2022-11-08T00:00:00.000Z","cpc_codes":["G01N","C12Q","G01N","G01N"],"num_claims":21,"abstract":"The invention relates to assays for nucleosome remodeling activity using functionalized recombinant mononucleosomes. The functionalized recombinant mononucleosomes comprise a histone octamer comprising recombinant histone H2A, H2B, H3 and H4 proteins and a DNA template comprising a nucleosome positioning sequence that effectively positions the histone octamer and a signal site. The invention further relates to methods of using the assay to quantify enzymatic activity of remodeling enzymes and identifying modulators of remodeling enzyme activity."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Assays for nucleosome remodeling activity","description":"The invention relates to assays for nucleosome remodeling activity using functionalized recombinant mononucleosomes. The functionalized recombinant mononucleosomes comprise a histone octamer comprisin","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11493520","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11493520","citation_suggestion":"Patentable. \"Assays for nucleosome remodeling activity\" (US-11493520). https://patentable.app/patents/US-11493520","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11493520","json":"https://patentable.app/api/llm-context/US-11493520","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T00:37:12.821Z"}