{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11498051","patent":{"patent_number":"US-11498051","title":"Method for preparing a monolithic stationary phase, associated method for producing a chromatography column and associated separation method","assignee":null,"inventors":[],"filing_date":"2018-07-05T00:00:00.000Z","publication_date":"2022-11-15T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N"],"num_claims":15,"abstract":"The invention relates to a method for preparing a monolithic stationary phase in the interior volume of a chromatography column made of thermoplastic polymer. This method comprises the following steps: (i) modifying the inner wall of the chromatography column by implementing the following steps: (a) preparing a polymerizable anchoring composition comprising at least one particular methacrylate monomer, one or more solvents and 2,2-dimethoxy-2-phenylacetophenone, (b) depositing, on the inner wall of the column, the polymerizable anchoring composition prepared in step (a), and (c) polymerizing the polymerizable anchoring composition by irradiation with ultraviolet radiation; (ii) introducing, into the interior volume of the column, a polymerizable monolith synthesis composition comprising first and second particular (meth)acrylate monomers, one or more pore-forming agents and a free-radical polymerization initiator; and (iii) polymerizing the polymerizable monolith synthesis composition. The invention also relates to a method for producing a chromatography column comprising such a monolithic stationary phase and to a chromatographic separation method using such a column."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method for preparing a monolithic stationary phase, associated method for producing a chromatography column and associated separation method","description":"The invention relates to a method for preparing a monolithic stationary phase in the interior volume of a chromatography column made of thermoplastic polymer. This method comprises the following steps","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11498051","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11498051","citation_suggestion":"Patentable. \"Method for preparing a monolithic stationary phase, associated method for producing a chromatography column and associated separation method\" (US-11498051). https://patentable.app/patents/US-11498051","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11498051","json":"https://patentable.app/api/llm-context/US-11498051","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T04:41:44.716Z"}