{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11945807","patent":{"patent_number":"US-11945807","title":"Splicing modulator antibody-drug conjugates and methods of use","assignee":null,"inventors":[],"filing_date":"2022-05-03T00:00:00.000Z","publication_date":"2024-04-02T00:00:00.000Z","cpc_codes":["C12Q","G01N","G01N","C12Q","G01N"],"num_claims":24,"abstract":"Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein. In an embodiment, the splicing modulator comprises a pladienolide or a pladienolide derivative."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Splicing modulator antibody-drug conjugates and methods of use","description":"Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11945807","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11945807","citation_suggestion":"Patentable. \"Splicing modulator antibody-drug conjugates and methods of use\" (US-11945807). https://patentable.app/patents/US-11945807","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11945807","json":"https://patentable.app/api/llm-context/US-11945807","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T01:50:47.114Z"}