{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11946854","patent":{"patent_number":"US-11946854","title":"Systems and methods for two-dimensional fluorescence wave propagation onto surfaces using deep learning","assignee":null,"inventors":[],"filing_date":"2019-12-23T00:00:00.000Z","publication_date":"2024-04-02T00:00:00.000Z","cpc_codes":["G01N","G01N","G06F","G06N","G06T","G06T","G06T","G06T","G06T","G06V","G06V","G06V","G06V","G01N","G01N","G06T","G06T","G06T","G06T","G06T","G06T"],"num_claims":22,"abstract":"A fluorescence microscopy method includes a trained deep neural network. At least one 2D fluorescence microscopy image of a sample is input to the trained deep neural network, wherein the input image(s) is appended with a digital propagation matrix (DPM) that represents, pixel-by-pixel, an axial distance of a user-defined or automatically generated surface within the sample from a plane of the input image. The trained deep neural network outputs fluorescence output image(s) of the sample that is digitally propagated or refocused to the user-defined surface or automatically generated. The method and system cross-connects different imaging modalities, permitting 3D propagation of wide-field fluorescence image(s) to match confocal microscopy images at different sample planes. The method may be used to output a time sequence of images (e.g., time-lapse video) of a 2D or 3D surface within a sample."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Systems and methods for two-dimensional fluorescence wave propagation onto surfaces using deep learning","description":"A fluorescence microscopy method includes a trained deep neural network. At least one 2D fluorescence microscopy image of a sample is input to the trained deep neural network, wherein the input image(","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11946854","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11946854","citation_suggestion":"Patentable. \"Systems and methods for two-dimensional fluorescence wave propagation onto surfaces using deep learning\" (US-11946854). https://patentable.app/patents/US-11946854","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11946854","json":"https://patentable.app/api/llm-context/US-11946854","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T03:22:55.536Z"}