{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11958915","patent":{"patent_number":"US-11958915","title":"Methods for treatment and diagnosis of non-alcoholic steatohepatitis and/or hepatocellular carcinoma","assignee":null,"inventors":[],"filing_date":"2021-04-06T00:00:00.000Z","publication_date":"2024-04-16T00:00:00.000Z","cpc_codes":["C12Q","G01N","G01N","G01N","G01N"],"num_claims":7,"abstract":"Methods for treating non-alcoholic steatohepatitis and/or hepatocellular carcinoma include administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof. Methods and assays for diagnosis or prognosis of non-alcoholic steatohepatitis and/or hepatocellular carcinoma in a subject are also provided and include the steps of providing a biological sample from the subject, determining an expression level or activity in the sample of at least one biomarker selected from Caveolin-1, Survivin, and SMAC; and comparing the expression level or activity of the at least one biomarker in the sample, if present, to a control expression level or activity of the at least one biomarker. Prophylaxis or treatment of the non-alcoholic steatohepatitis and/or hepatocellular carcinoma in a subject can then be initiated based on the expression level or activity of Caveolin-1, Survivin, and SMAC in the sample."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Methods for treatment and diagnosis of non-alcoholic steatohepatitis and/or hepatocellular carcinoma","description":"Methods for treating non-alcoholic steatohepatitis and/or hepatocellular carcinoma include administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof. Me","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11958915","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11958915","citation_suggestion":"Patentable. \"Methods for treatment and diagnosis of non-alcoholic steatohepatitis and/or hepatocellular carcinoma\" (US-11958915). https://patentable.app/patents/US-11958915","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11958915","json":"https://patentable.app/api/llm-context/US-11958915","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T02:40:48.929Z"}