{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11965889","patent":{"patent_number":"US-11965889","title":"Lysine monomethylated derivative and corresponding antibody and use thereof","assignee":null,"inventors":[],"filing_date":"2020-01-22T00:00:00.000Z","publication_date":"2024-04-23T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N"],"num_claims":1,"abstract":"The present invention relates to artificially synthesized modified mono-methylated lysines and modified mono-methylated lysine derivatized polypeptides. The present invention also relates to production of a completely new antibody by using this modified mono-methylated lysine and modified mono-methylated lysine derivatized polypeptide as an antigen, this antibody can be used in recognizing and enriching the modified polypeptide after the lysine mono-methylated polypeptide being derivatized in vitro. By using this antibody, it is capable of detecting whether a mono-methylation modification is present in amino acids on the polypeptide sequence, the present invention also relates to a preparation method of said antibody. Moreover, the present invention also relates to a method for identifying and quantifying the lysine mono-methylated modified substrate in cell or tissue; more specifically, it belongs to identifying and quantifying the lysine mono-methylated modified substrate in cell or tissue by using proteomics approach of affinity enrichment for specific antibody and mass spectrometry."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Lysine monomethylated derivative and corresponding antibody and use thereof","description":"The present invention relates to artificially synthesized modified mono-methylated lysines and modified mono-methylated lysine derivatized polypeptides. The present invention also relates to productio","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11965889","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11965889","citation_suggestion":"Patentable. \"Lysine monomethylated derivative and corresponding antibody and use thereof\" (US-11965889). https://patentable.app/patents/US-11965889","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11965889","json":"https://patentable.app/api/llm-context/US-11965889","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T12:19:34.564Z"}