{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-11990209","patent":{"patent_number":"US-11990209","title":"Identification of instance-specific somatic genome alterations with functional impact","assignee":null,"inventors":[],"filing_date":"2017-11-13T00:00:00.000Z","publication_date":"2024-05-21T00:00:00.000Z","cpc_codes":["G16B","G16B","G16B","G16B","G16B","G16B","G16B"],"num_claims":20,"abstract":"The present application provides methods for the identification of somatic genome alterations with functional impact in the genome of a tumor. In several embodiments, the methods comprise generating a bipartite causal Bayesian network with maximal posterior probability including causal edges pointing from genes including somatic mutations and somatic copy number alterations in the genome of the tumor to genes having differential expression in the tumor. The methods can be used, for example, to identify driver somatic genome alterations in the genome of a tumor."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Identification of instance-specific somatic genome alterations with functional impact","description":"The present application provides methods for the identification of somatic genome alterations with functional impact in the genome of a tumor. In several embodiments, the methods comprise generating a","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-11990209","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-11990209","citation_suggestion":"Patentable. \"Identification of instance-specific somatic genome alterations with functional impact\" (US-11990209). https://patentable.app/patents/US-11990209","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-11990209","json":"https://patentable.app/api/llm-context/US-11990209","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T12:47:53.976Z"}