{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-12000002","patent":{"patent_number":"US-12000002","title":"Pre-surgical risk stratification based on PDE4D7 expression and pre-surgical clinical variables","assignee":null,"inventors":[],"filing_date":"2018-12-19T00:00:00.000Z","publication_date":"2024-06-04T00:00:00.000Z","cpc_codes":["C12Q","G16B","G16B","G16H","C12Q","C12Q","C12Q"],"num_claims":13,"abstract":"The invention relates to a method of pre-surgical risk stratification of a prostate cancer subject, comprising determining a gene expression profile for phosphodiesterase 4D variant 7 (PDE4D7) in a biological sample obtained from the subject, determining gene expression profile, and determining a pre-surgical prognostic risk score for the subject based on the expression based risk score and pre-surgical clinical variables of the subject. This may allow for an improved stratification of the subject in a pre-surgical setting that may result in better primary treatment decisions. For instance, the pre-surgical prognostic risk score may allow to make better recommendation on whether to select active surveillance vs. active intervention, e.g., radical prostatectomy, for certain sub-populations of prostate cancer patients."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Pre-surgical risk stratification based on PDE4D7 expression and pre-surgical clinical variables","description":"The invention relates to a method of pre-surgical risk stratification of a prostate cancer subject, comprising determining a gene expression profile for phosphodiesterase 4D variant 7 (PDE4D7) in a bi","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-12000002","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-12000002","citation_suggestion":"Patentable. \"Pre-surgical risk stratification based on PDE4D7 expression and pre-surgical clinical variables\" (US-12000002). https://patentable.app/patents/US-12000002","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-12000002","json":"https://patentable.app/api/llm-context/US-12000002","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T07:15:53.352Z"}