{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-12006549","patent":{"patent_number":"US-12006549","title":"Methods utilizing leukocyte RNA expression in prognosis evaluation of medical interventions for epilepsy","assignee":null,"inventors":[],"filing_date":"2019-10-04T00:00:00.000Z","publication_date":"2024-06-11T00:00:00.000Z","cpc_codes":["C12Q","C12Q","A61N","C12Q","G01N","G01N"],"num_claims":4,"abstract":"Methods involving analysis of pretreatment leukocyte expression profiles for prognostic assessment of seizure outcome following a treatment or medical procedure, such as stereotactic laser amygdalohippocampotomy (SLAH). In one aspect, RNA sequencing (RNA-Seq) on whole blood leukocyte samples is taken from a patient with intractable epilepsy prior to SLAH. Differential expression (DE) analysis revealed 24 significantly dysregulated genes (≥2.0-fold change, p-value <0.05, and False Discovery Rate, FDR <0.05) useful in prognostic assessment."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Methods utilizing leukocyte RNA expression in prognosis evaluation of medical interventions for epilepsy","description":"Methods involving analysis of pretreatment leukocyte expression profiles for prognostic assessment of seizure outcome following a treatment or medical procedure, such as stereotactic laser amygdalohip","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-12006549","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-12006549","citation_suggestion":"Patentable. \"Methods utilizing leukocyte RNA expression in prognosis evaluation of medical interventions for epilepsy\" (US-12006549). https://patentable.app/patents/US-12006549","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-12006549","json":"https://patentable.app/api/llm-context/US-12006549","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T12:20:38.440Z"}