{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8460875","patent":{"patent_number":"US-8460875","title":"Recombinase polymerase amplification","assignee":null,"inventors":[],"filing_date":"2011-07-28T00:00:00.000Z","publication_date":"2013-06-11T00:00:00.000Z","cpc_codes":["C12Q","C12Q","C12Q","C12Q","G06F","G06F"],"num_claims":21,"abstract":"This disclosure provides methods for Recombinase-Polymerase Amplification (RPA) of a target DNA. The methods exploit the properties of the bacterial RecA and related proteins to invade double-stranded DNA with single stranded homologous DNA permitting sequence specific priming of DNA polymerase reactions. The methods have the advantage of not requiring thermocycling or thermophilic enzymes. Further, the methods allow amplification of DNA up to hundreds of megabases in length."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Recombinase polymerase amplification","description":"This disclosure provides methods for Recombinase-Polymerase Amplification (RPA) of a target DNA. The methods exploit the properties of the bacterial RecA and related proteins to invade double-stranded","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8460875","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8460875","citation_suggestion":"Patentable. \"Recombinase polymerase amplification\" (US-8460875). https://patentable.app/patents/US-8460875","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8460875","json":"https://patentable.app/api/llm-context/US-8460875","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T04:23:58.679Z"}