{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8465916","patent":{"patent_number":"US-8465916","title":"Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments","assignee":null,"inventors":[],"filing_date":"2007-08-20T00:00:00.000Z","publication_date":"2013-06-18T00:00:00.000Z","cpc_codes":["C12Q","C12Q","G01N","G01N","C12Q","C12Q","C12Q","C12Q","C12Q","C12Q","G01N","G01N"],"num_claims":21,"abstract":"The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments","description":"The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8465916","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8465916","citation_suggestion":"Patentable. \"Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments\" (US-8465916). https://patentable.app/patents/US-8465916","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8465916","json":"https://patentable.app/api/llm-context/US-8465916","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T13:41:30.500Z"}