{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8466160","patent":{"patent_number":"US-8466160","title":"Identification of non-small cell lung carcinoma (NSCLC) tumors expressing PDGFR-alpha","assignee":null,"inventors":[],"filing_date":"2010-12-30T00:00:00.000Z","publication_date":"2013-06-18T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N"],"num_claims":10,"abstract":"The invention discloses a previously unidentified subset of mammalian non-small cell lung carcinomas (NSCLC) in which platelet-derived growth factor receptor alpha (PDGFRα) is expressed and is driving the disease, and provides methods for identifying a mammalian NSCLC tumor that belongs to a subset of NSCLC tumors in which PDGFRα is expressed, and for identifying a NSCLC tumor that is likely to respond to a PDGFRα-inhibiting therapeutic. The invention also provides methods for inhibiting the progression of a mammalian NSCLC tumor in which PDGFRα is expressed, and for determining whether a compound inhibits the progression of a PDGFRα-expressing mammalian NSCLC tumor."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Identification of non-small cell lung carcinoma (NSCLC) tumors expressing PDGFR-alpha","description":"The invention discloses a previously unidentified subset of mammalian non-small cell lung carcinomas (NSCLC) in which platelet-derived growth factor receptor alpha (PDGFRα) is expressed and is driving","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8466160","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8466160","citation_suggestion":"Patentable. \"Identification of non-small cell lung carcinoma (NSCLC) tumors expressing PDGFR-alpha\" (US-8466160). https://patentable.app/patents/US-8466160","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8466160","json":"https://patentable.app/api/llm-context/US-8466160","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T22:34:18.299Z"}