{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8470321","patent":{"patent_number":"US-8470321","title":"Antibodies specific for the protofibril form of beta-amyloid protein","assignee":null,"inventors":[],"filing_date":"2008-11-14T00:00:00.000Z","publication_date":"2013-06-25T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N"],"num_claims":18,"abstract":"Isolated antibodies have been characterized which show specific affinity to a repeating conformational epitope of a protofibril form of the human β-amyloid peptide as compare to low molecular weight forms of β-amyloid peptide. These isolated antibodies and related pharmaceutically effective compositions may be useful in the therapeutic and/or prophylactic treatment of Alzheimer's disease by effectively blocking the ability of the protofibril form of β-amyloid peptide to form fibril forms linked with complications associated with Alzheimer's disease. The isolated antibodies of the present invention are also useful in various diagnostic assays and associated kits."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Antibodies specific for the protofibril form of beta-amyloid protein","description":"Isolated antibodies have been characterized which show specific affinity to a repeating conformational epitope of a protofibril form of the human β-amyloid peptide as compare to low molecular weight f","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8470321","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8470321","citation_suggestion":"Patentable. \"Antibodies specific for the protofibril form of beta-amyloid protein\" (US-8470321). https://patentable.app/patents/US-8470321","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8470321","json":"https://patentable.app/api/llm-context/US-8470321","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T01:55:08.765Z"}