{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8470534","patent":{"patent_number":"US-8470534","title":"Methods of predicting resistance or sensitivity to therapies for cancer","assignee":null,"inventors":[],"filing_date":"2007-12-03T00:00:00.000Z","publication_date":"2013-06-25T00:00:00.000Z","cpc_codes":["C12Q","G01N","C12Q","C12Q"],"num_claims":9,"abstract":"The present application is directed to methods of predicting the resistance of a tumor to molecularly targeted therapy and methods of predicting sensitivity of a tumor to DNA damaging therapy. The methods include: a) determining the level of expression of plurality of genes regulated by retinoblastoma tumor supressor (RB) in the individual, and b) comparing the level of expression of the plurality of genes regulated by RB in the individual with a level of expression of the plurality of genes regulated by RB in a control. The application is also directed to an RNA expression profile for the loss of RB."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Methods of predicting resistance or sensitivity to therapies for cancer","description":"The present application is directed to methods of predicting the resistance of a tumor to molecularly targeted therapy and methods of predicting sensitivity of a tumor to DNA damaging therapy. The met","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8470534","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8470534","citation_suggestion":"Patentable. \"Methods of predicting resistance or sensitivity to therapies for cancer\" (US-8470534). https://patentable.app/patents/US-8470534","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8470534","json":"https://patentable.app/api/llm-context/US-8470534","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T21:20:10.847Z"}