{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8470974","patent":{"patent_number":"US-8470974","title":"Method for highly sensitive detection of protein-protein interaction","assignee":null,"inventors":[],"filing_date":"2010-05-28T00:00:00.000Z","publication_date":"2013-06-25T00:00:00.000Z","cpc_codes":["C12Q","C12Q","G01N"],"num_claims":13,"abstract":"The present invention intends to provide an assay system using split luciferase that has a remarkably high detection sensitivity. In an embodiment, binding of mutually binding first and second proteins is detected by preparing a first fusion protein comprising the first protein fused with a peptide having the amino acid sequence of amino acid SEQ ID NO: 1 and a second fusion protein comprising the second protein fused with a peptide having an amino acid sequence selected from the group consisting of amino acid SEQ ID NOS: 2 to 6, and allowing the first fusion protein to bind with the second fusion protein to form a complex, and detecting luminescence emitted from the complex."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method for highly sensitive detection of protein-protein interaction","description":"The present invention intends to provide an assay system using split luciferase that has a remarkably high detection sensitivity. In an embodiment, binding of mutually binding first and second protein","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8470974","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8470974","citation_suggestion":"Patentable. \"Method for highly sensitive detection of protein-protein interaction\" (US-8470974). https://patentable.app/patents/US-8470974","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8470974","json":"https://patentable.app/api/llm-context/US-8470974","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T17:16:40.356Z"}