{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8476023","patent":{"patent_number":"US-8476023","title":"Methods relating to aromatase inhibitor pharmacogenetics","assignee":null,"inventors":[],"filing_date":"2010-08-09T00:00:00.000Z","publication_date":"2013-07-02T00:00:00.000Z","cpc_codes":["C12Q","C12Q","C12Q","C12Q","C12Q","C12Q","G01N"],"num_claims":18,"abstract":"Methods for aiding in determining therapeutic efficacy of an aromatase inhibitor in a subject are provided according to embodiments of the present invention which include detecting expression and/or function of at least one UDP-glucuronosyltransferase having activity to modify at least one aromatase inhibitor and/or metabolite of the aromatase inhibitor by glucuronidation, wherein detection of expression and/or function of the UDP-glucuronosyltransferase is correlated with therapeutic efficacy of the aromatase inhibitor in the subject. Detection of UDP-glucuronosyltransferase expression and/or function includes detection of a UDP-glucuronosyltransferase gene deletion polymorphism in the subject."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Methods relating to aromatase inhibitor pharmacogenetics","description":"Methods for aiding in determining therapeutic efficacy of an aromatase inhibitor in a subject are provided according to embodiments of the present invention which include detecting expression and/or f","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8476023","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8476023","citation_suggestion":"Patentable. \"Methods relating to aromatase inhibitor pharmacogenetics\" (US-8476023). https://patentable.app/patents/US-8476023","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8476023","json":"https://patentable.app/api/llm-context/US-8476023","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T07:47:05.417Z"}