{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8476025","patent":{"patent_number":"US-8476025","title":"ATM-dependent phosphorylation of Sp1 is involved in the cellular response to DNA damage and enhances cellular survival after DNA damage","assignee":null,"inventors":[],"filing_date":"2008-08-06T00:00:00.000Z","publication_date":"2013-07-02T00:00:00.000Z","cpc_codes":["G01N","G01N"],"num_claims":5,"abstract":"The present invention is related to the discovery that phosphorylation of SP1 (SEQ ID NO.: 2) at serine residue 101 (known herein as phosphoserine101 Sp1) is an important part of a cell's response to DNA damage. This phosphorylation event is important for subsequent Sp1 localization to a site of DNA damage and is correlated with increased cellular viability in response to DNA damage."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"ATM-dependent phosphorylation of Sp1 is involved in the cellular response to DNA damage and enhances cellular survival after DNA damage","description":"The present invention is related to the discovery that phosphorylation of SP1 (SEQ ID NO.: 2) at serine residue 101 (known herein as phosphoserine101 Sp1) is an important part of a cell's response to ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8476025","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8476025","citation_suggestion":"Patentable. \"ATM-dependent phosphorylation of Sp1 is involved in the cellular response to DNA damage and enhances cellular survival after DNA damage\" (US-8476025). https://patentable.app/patents/US-8476025","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8476025","json":"https://patentable.app/api/llm-context/US-8476025","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T15:38:03.006Z"}