{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8478535","patent":{"patent_number":"US-8478535","title":"Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails","assignee":null,"inventors":[],"filing_date":"2005-12-30T00:00:00.000Z","publication_date":"2013-07-02T00:00:00.000Z","cpc_codes":["G16B","G16B","G16B","G16B","G16B","G16B","G16B","G06N","G16B","G16B"],"num_claims":47,"abstract":"The subject invention provides systems and methods that facilitate AIDS vaccine cocktail assembly via machine learning algorithms such as a cost function, a greedy algorithm, an expectation-maximization (EM) algorithm, etc. Such assembly can be utilized to generate vaccine cocktails for species of pathogens that evolve quickly under immune pressure of the host. For example, the systems and methods of the subject invention can be utilized to facilitate design of T cell vaccines for pathogens such HIV. In addition, the systems and methods of the subject invention can be utilized in connection with other applications, such as, for example, sequence alignment, motif discovery, classification, and recombination hot spot detection. The novel techniques described herein can provide for improvements over traditional approaches to designing vaccines by constructing vaccine cocktails with higher epitope coverage, for example, in comparison with cocktails of consensi, tree nodes and random strains from data."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails","description":"The subject invention provides systems and methods that facilitate AIDS vaccine cocktail assembly via machine learning algorithms such as a cost function, a greedy algorithm, an expectation-maximizati","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8478535","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8478535","citation_suggestion":"Patentable. \"Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails\" (US-8478535). https://patentable.app/patents/US-8478535","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8478535","json":"https://patentable.app/api/llm-context/US-8478535","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T20:58:41.301Z"}