{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8478544","patent":{"patent_number":"US-8478544","title":"Direct identification and measurement of relative populations of microorganisms with direct DNA sequencing and probabilistic methods","assignee":null,"inventors":[],"filing_date":"2011-01-26T00:00:00.000Z","publication_date":"2013-07-02T00:00:00.000Z","cpc_codes":["G16B","G16B","G16B","G16B","G16B","G16B","G16H","C12Q","G16B"],"num_claims":49,"abstract":"The present invention relates to systems and methods capable of characterizing populations of organisms within a sample. The characterization may utilize probabilistic matching of short strings of sequencing information to identify genomes from a reference genomic database to which the short strings belong. The characterization may include identification of the microbial community of the sample to the species and/or sub-species and/or strain level with their relative concentrations or abundance. In addition, the system and methods may enable rapid identification of organisms including both pathogens and commensals in clinical samples, and the identification may be achieved by a comparison of many (e.g., hundreds to millions) metagenomic fragments, which have been captured from a sample and sequenced, to many (e.g., millions or billions) of archived sequence information of genomes (i.e., reference genomic databases)."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Direct identification and measurement of relative populations of microorganisms with direct DNA sequencing and probabilistic methods","description":"The present invention relates to systems and methods capable of characterizing populations of organisms within a sample. The characterization may utilize probabilistic matching of short strings of seq","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8478544","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8478544","citation_suggestion":"Patentable. \"Direct identification and measurement of relative populations of microorganisms with direct DNA sequencing and probabilistic methods\" (US-8478544). https://patentable.app/patents/US-8478544","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8478544","json":"https://patentable.app/api/llm-context/US-8478544","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T16:21:28.918Z"}