{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8491891","patent":{"patent_number":"US-8491891","title":"Human beta-glucuronidase mutants with elevated enzymatic activity under physiological conditions and method for identifying such","assignee":null,"inventors":[],"filing_date":"2009-11-25T00:00:00.000Z","publication_date":"2013-07-23T00:00:00.000Z","cpc_codes":["C12Q","G01N","G01N"],"num_claims":11,"abstract":"A number of human beta-glucuronidase variants having higher enzymatic activity at physiological pH as compared with wild-type beta-glucuronidase and uses thereof in prodrug therapy. Also disclosed herein is a method for identifying enzyme variants having elevated enzymatic activity using a mammalian surface display system."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Human beta-glucuronidase mutants with elevated enzymatic activity under physiological conditions and method for identifying such","description":"A number of human beta-glucuronidase variants having higher enzymatic activity at physiological pH as compared with wild-type beta-glucuronidase and uses thereof in prodrug therapy. Also disclosed her","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8491891","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8491891","citation_suggestion":"Patentable. \"Human beta-glucuronidase mutants with elevated enzymatic activity under physiological conditions and method for identifying such\" (US-8491891). https://patentable.app/patents/US-8491891","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8491891","json":"https://patentable.app/api/llm-context/US-8491891","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T19:51:16.013Z"}