{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8491907","patent":{"patent_number":"US-8491907","title":"Human anti-Pseudomonas-aeruginosa It-2 antibodies derived from transgenic xenomouse","assignee":null,"inventors":[],"filing_date":"2010-07-13T00:00:00.000Z","publication_date":"2013-07-23T00:00:00.000Z","cpc_codes":["G01N","G01N"],"num_claims":2,"abstract":"The invention described herein provides for human antibodies produced in non-human animals that specifically bind to lipopolysaccharide (LPS) from strains Fisher Devlin (International Serogroups) It-2 (011), It-3 (02), It-4 (01), It-5 (010), It-6 (07), PA01 (05), 170003 (02), IATS016 (02/05), and 170006 (02). The invention further provides methods for making the antibodies in a non-human animal, expression of the antibodies in cell lines including hybridomas and recombinant host cell systems. Also provided are kits and pharmaceutical compositions comprising the antibodies and methods of treating or preventing pseudomonas infection by administering to a patient the pharmaceutical compositions described herein."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Human anti-Pseudomonas-aeruginosa It-2 antibodies derived from transgenic xenomouse","description":"The invention described herein provides for human antibodies produced in non-human animals that specifically bind to lipopolysaccharide (LPS) from strains Fisher Devlin (International Serogroups) It-2","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8491907","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8491907","citation_suggestion":"Patentable. \"Human anti-Pseudomonas-aeruginosa It-2 antibodies derived from transgenic xenomouse\" (US-8491907). https://patentable.app/patents/US-8491907","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8491907","json":"https://patentable.app/api/llm-context/US-8491907","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T23:29:56.907Z"}