{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8492090","patent":{"patent_number":"US-8492090","title":"Gene expression profiling in primary ovarian serous papillary tumors and normal ovarian epithelium","assignee":null,"inventors":[],"filing_date":"2011-04-04T00:00:00.000Z","publication_date":"2013-07-23T00:00:00.000Z","cpc_codes":["G01N","C12Q","C12Q"],"num_claims":3,"abstract":"Provided herein are methods for treating ovarian serous papillary carcinoma by delivering Clostridium perfringens enterotoxins to ovarian tumor cells overexpressing claudin 3 or claudin 4 protein or by inhibiting the expression and function of tumor-associated calcium signal transducer 1 (TROP-1/Ep-CAM) gene or gene product. Also provided is a method of detecting ovarian serous papillary carcinoma by examining a tumor sample from the individual for gene or gene product expression levels within a group of genes and performing statistical analysis to determine those genes or gene products which are down-regulated compared to those in a normal individual."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Gene expression profiling in primary ovarian serous papillary tumors and normal ovarian epithelium","description":"Provided herein are methods for treating ovarian serous papillary carcinoma by delivering Clostridium perfringens enterotoxins to ovarian tumor cells overexpressing claudin 3 or claudin 4 protein or b","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8492090","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8492090","citation_suggestion":"Patentable. \"Gene expression profiling in primary ovarian serous papillary tumors and normal ovarian epithelium\" (US-8492090). https://patentable.app/patents/US-8492090","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8492090","json":"https://patentable.app/api/llm-context/US-8492090","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T18:50:46.931Z"}