{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8497089","patent":{"patent_number":"US-8497089","title":"Method to predict toxicity using the analysis of dynamic organelle behaviour","assignee":null,"inventors":[],"filing_date":"2008-09-10T00:00:00.000Z","publication_date":"2013-07-30T00:00:00.000Z","cpc_codes":["G01N","G01N"],"num_claims":22,"abstract":"The present invention provides an in vitro method to predict the effect of an exogenous element on an animal or human organism. This method is based on the analysis of variations of an organelle behaviour represented by at least two characteristics in isolated cells induced by the contact with the exogenous element and the determination of the cluster membership of the exogenous element which is representative of the effect of said element. Analyzed characteristics are selected from the group consisting of the motility, the morphology, the relationship with the cell cytoskeleton and the membrane permeability of said organelle. This method may be used to predict the efficacy or the toxicity of an element, such as a drug."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method to predict toxicity using the analysis of dynamic organelle behaviour","description":"The present invention provides an in vitro method to predict the effect of an exogenous element on an animal or human organism. This method is based on the analysis of variations of an organelle behav","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8497089","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8497089","citation_suggestion":"Patentable. \"Method to predict toxicity using the analysis of dynamic organelle behaviour\" (US-8497089). https://patentable.app/patents/US-8497089","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8497089","json":"https://patentable.app/api/llm-context/US-8497089","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T19:50:35.999Z"}