{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8497361","patent":{"patent_number":"US-8497361","title":"Topoisomerase binding probe and method of use","assignee":null,"inventors":[],"filing_date":"2011-08-22T00:00:00.000Z","publication_date":"2013-07-30T00:00:00.000Z","cpc_codes":["C12Q","G01N","G01N"],"num_claims":20,"abstract":"An aminocoumarin conjugated to a fluorescent label through a secondary amine, is operative as a fluorescent polarization probe of the DNA gyrase B or topoisomerase IV E subunit. The probe is used for detecting topoisomerase inhibitor binding by fluorescence polarization, particularly in a high-through put topoisomerase inhibitor assay."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Topoisomerase binding probe and method of use","description":"An aminocoumarin conjugated to a fluorescent label through a secondary amine, is operative as a fluorescent polarization probe of the DNA gyrase B or topoisomerase IV E subunit. The probe is used for ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8497361","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8497361","citation_suggestion":"Patentable. \"Topoisomerase binding probe and method of use\" (US-8497361). https://patentable.app/patents/US-8497361","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8497361","json":"https://patentable.app/api/llm-context/US-8497361","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-31T03:15:13.798Z"}