{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8501415","patent":{"patent_number":"US-8501415","title":"Identification of TSH receptor autoantibodies using affinity-purified antibodies","assignee":null,"inventors":[],"filing_date":"2003-10-31T00:00:00.000Z","publication_date":"2013-08-06T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N","G01N"],"num_claims":5,"abstract":"The present invention relates to the use of affinity-purified polyclonal human autoantibodies against the TSH receptor (TSHR-Auto-Ab), obtained from the serum of Graves' disease patients and which have been purified to obtain biochemical homogeneity and comprise a specific activity of at least 1 IU/mg protein (human immunoglobulin). Also disclosed is the use of animal antibodies, which compete with the former for the binding sites of a functional human TSH receptor, as a specific binding reagent in an immunological determination method for the clinical identification of autoantibodies against the TSH receptor (TSHR-Auto-Ab) in a sample of a biological fluid of a patient to be examined for Graves' disease."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Identification of TSH receptor autoantibodies using affinity-purified antibodies","description":"The present invention relates to the use of affinity-purified polyclonal human autoantibodies against the TSH receptor (TSHR-Auto-Ab), obtained from the serum of Graves' disease patients and which hav","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8501415","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8501415","citation_suggestion":"Patentable. \"Identification of TSH receptor autoantibodies using affinity-purified antibodies\" (US-8501415). https://patentable.app/patents/US-8501415","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8501415","json":"https://patentable.app/api/llm-context/US-8501415","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T22:12:20.981Z"}