{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8501465","patent":{"patent_number":"US-8501465","title":"Modulators of alpha-synuclein toxicity","assignee":null,"inventors":[],"filing_date":"2008-12-22T00:00:00.000Z","publication_date":"2013-08-06T00:00:00.000Z","cpc_codes":["C12Q","C12Q","G01N","C12Q","C12Q","G01N","G01N"],"num_claims":7,"abstract":"Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Modulators of alpha-synuclein toxicity","description":"Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these gen","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8501465","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8501465","citation_suggestion":"Patentable. \"Modulators of alpha-synuclein toxicity\" (US-8501465). https://patentable.app/patents/US-8501465","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8501465","json":"https://patentable.app/api/llm-context/US-8501465","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T16:55:39.497Z"}