{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8518643","patent":{"patent_number":"US-8518643","title":"Method to improve single molecule analyses","assignee":null,"inventors":[],"filing_date":"2011-02-01T00:00:00.000Z","publication_date":"2013-08-27T00:00:00.000Z","cpc_codes":["C12Q","C12Q","C12Q","C12Q","G01N","G01N","G01N","G01N","C12Q"],"num_claims":22,"abstract":"The quality of information from single molecule analyses is improved by employing a method in which a single molecule reaction carried out within an optical confinement is monitored, the single molecule reaction is halted, and data from the optical confinement is obtained while the reaction is not occurring. Characteristic optical behavior observed while the reaction is halted is used to improve the quality of information obtained during the single molecule reaction, for example, by correcting the reaction data, excluding the reaction data, or providing a confidence level to the reaction data."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method to improve single molecule analyses","description":"The quality of information from single molecule analyses is improved by employing a method in which a single molecule reaction carried out within an optical confinement is monitored, the single molecu","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8518643","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8518643","citation_suggestion":"Patentable. \"Method to improve single molecule analyses\" (US-8518643). https://patentable.app/patents/US-8518643","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8518643","json":"https://patentable.app/api/llm-context/US-8518643","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T17:13:00.707Z"}