{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8518657","patent":{"patent_number":"US-8518657","title":"Method of prognosing and diagnosing hereditary spastic paraplegia, mutant nucleic acid molecules and polypeptides","assignee":null,"inventors":[],"filing_date":"2011-05-18T00:00:00.000Z","publication_date":"2013-08-27T00:00:00.000Z","cpc_codes":["G01N","C12Q","C12Q","C12Q","C12Q","G01N"],"num_claims":24,"abstract":"A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a gene encoding a polypeptide comprising the sequence of FIG. 9 (SEQ ID NO: 19), in a nucleic acid sample of the subject, whereby the detection of the defect is indicative that the subject has or is at risk of developing HSP."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method of prognosing and diagnosing hereditary spastic paraplegia, mutant nucleic acid molecules and polypeptides","description":"A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a g","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8518657","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8518657","citation_suggestion":"Patentable. \"Method of prognosing and diagnosing hereditary spastic paraplegia, mutant nucleic acid molecules and polypeptides\" (US-8518657). https://patentable.app/patents/US-8518657","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8518657","json":"https://patentable.app/api/llm-context/US-8518657","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T17:07:02.088Z"}