{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8524239","patent":{"patent_number":"US-8524239","title":"Photosensitizing antibody-fluorophore conjugates","assignee":null,"inventors":[],"filing_date":"2011-07-11T00:00:00.000Z","publication_date":"2013-09-03T00:00:00.000Z","cpc_codes":["A61N","G01N"],"num_claims":25,"abstract":"The present disclosure relates to compositions and methods of killing cells in vitro or in vivo. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein. In particular examples the antibody recognizes a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm−2, thereby killing the cell. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Photosensitizing antibody-fluorophore conjugates","description":"The present disclosure relates to compositions and methods of killing cells in vitro or in vivo. In particular examples, the method includes contacting a cell having a cell surface protein with a ther","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8524239","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8524239","citation_suggestion":"Patentable. \"Photosensitizing antibody-fluorophore conjugates\" (US-8524239). https://patentable.app/patents/US-8524239","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8524239","json":"https://patentable.app/api/llm-context/US-8524239","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T17:14:09.167Z"}