{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-8530408","patent":{"patent_number":"US-8530408","title":"Substrates of N-end rule ubiquitylation and methods for measuring the ubiquitylation of these substrate","assignee":null,"inventors":[],"filing_date":"2009-10-27T00:00:00.000Z","publication_date":"2013-09-10T00:00:00.000Z","cpc_codes":["G01N","C12Q","C12Q","G01N"],"num_claims":4,"abstract":"The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrates, enzymes and modulators of N-end rule ubiquitylation. The present invention also relates to specific substrates of N-end rule ubiquitylation as well as activated fragments of these substrates, proteases that expose N-degrons in these substrates, ubiquitin ligases that ubiquitylate these substrates and inhibitors of the ubiquitylation of these substrates."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Substrates of N-end rule ubiquitylation and methods for measuring the ubiquitylation of these substrate","description":"The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrate","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-8530408","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-8530408","citation_suggestion":"Patentable. \"Substrates of N-end rule ubiquitylation and methods for measuring the ubiquitylation of these substrate\" (US-8530408). https://patentable.app/patents/US-8530408","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-8530408","json":"https://patentable.app/api/llm-context/US-8530408","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-05-30T10:30:16.714Z"}