{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9607374","patent":{"patent_number":"US-9607374","title":"Color decomposition in histology","assignee":null,"inventors":[],"filing_date":"2012-11-09T00:00:00.000Z","publication_date":"2017-03-28T00:00:00.000Z","cpc_codes":["G06V","G06T","G06T","G06V","G06T","G06T","G06T"],"num_claims":25,"abstract":"The method according to the invention generates a color decomposition of histological tissue image data into density maps, where each density map corresponds to the portion of the original image data that contains one stain/tissue combination. After a microscope captures histological tissue image data from a tissue sample that has been stained with at least one stain, the said stain or stains being light absorbent, the method derives from the histological tissue image data a color mixing matrix with the columns of the matrix being color reference vectors. From this mixing matrix the method derives a density map, when the mixing matrix is well-conditioned, by applying a pseudo-inverse of the mixing matrix to the optical density data, and when the mixing matrix is medially-conditioned, by applying a piece-wise pseudo-inverse of the mixing matrix to the optical density data. The method according to the invention also generates stain/tissue combination efficacy measures."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Color decomposition in histology","description":"The method according to the invention generates a color decomposition of histological tissue image data into density maps, where each density map corresponds to the portion of the original image data ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9607374","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9607374","citation_suggestion":"Patentable. \"Color decomposition in histology\" (US-9607374). https://patentable.app/patents/US-9607374","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9607374","json":"https://patentable.app/api/llm-context/US-9607374","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T06:09:31.115Z"}