{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9619875","patent":{"patent_number":"US-9619875","title":"Contrast reagent leakage correction in dynamic susceptibility contrast magnetic resonance imaging","assignee":null,"inventors":[],"filing_date":"2015-04-23T00:00:00.000Z","publication_date":"2017-04-11T00:00:00.000Z","cpc_codes":["G06T","A61B","A61B","G06T","A61B","G06T","G06T","G06T","G06T","G06T","G06T","G16H"],"num_claims":17,"abstract":"Disclosed are methods and systems for calculating a contrast reagent (CR) extravasation rate constant and generating a contrast reagent leakage corrected relative cerebral blood volume (rCBV) image map of a brain region from dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) time-course image data based on pharmacokinetic first principles. In one example approach, a computerized method may include performing a linearization transform of a DSC MRI time-course equation which accounts for an intravascular contribution and an extravasating component, and calculating CR leakage from a slope of a linear portion of the transformed data."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Contrast reagent leakage correction in dynamic susceptibility contrast magnetic resonance imaging","description":"Disclosed are methods and systems for calculating a contrast reagent (CR) extravasation rate constant and generating a contrast reagent leakage corrected relative cerebral blood volume (rCBV) image ma","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9619875","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9619875","citation_suggestion":"Patentable. \"Contrast reagent leakage correction in dynamic susceptibility contrast magnetic resonance imaging\" (US-9619875). https://patentable.app/patents/US-9619875","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9619875","json":"https://patentable.app/api/llm-context/US-9619875","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T07:47:49.811Z"}