{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9637798","patent":{"patent_number":"US-9637798","title":"Genetic signature of vulnerability to inhibitors of base excision repair (BER) in cancer","assignee":null,"inventors":[],"filing_date":"2014-05-21T00:00:00.000Z","publication_date":"2017-05-02T00:00:00.000Z","cpc_codes":["C12Q","G01N","G01N","C12Q","C12Q","C12Q","C12Q","G01N","G01N"],"num_claims":10,"abstract":"The invention relates to the identification of genetic signatures and expression profiles that are a part of the Base Excision Repair (BER) pathway, a major DNA repair pathway that modifies base lesions. In one embodiment, the present invention provides a method of determining responsiveness of treatment by BER inhibitors for malignant glioma by determining the presence of a low level of expression of Apex 1, a low level of expression of Apex 2, and a high level of expression of MPG."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Genetic signature of vulnerability to inhibitors of base excision repair (BER) in cancer","description":"The invention relates to the identification of genetic signatures and expression profiles that are a part of the Base Excision Repair (BER) pathway, a major DNA repair pathway that modifies base lesio","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9637798","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9637798","citation_suggestion":"Patentable. \"Genetic signature of vulnerability to inhibitors of base excision repair (BER) in cancer\" (US-9637798). https://patentable.app/patents/US-9637798","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9637798","json":"https://patentable.app/api/llm-context/US-9637798","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T07:16:09.982Z"}