{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9653272","patent":{"patent_number":"US-9653272","title":"Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies","assignee":null,"inventors":[],"filing_date":"2013-03-15T00:00:00.000Z","publication_date":"2017-05-16T00:00:00.000Z","cpc_codes":["G01N","G01N","G16B","G16B","G16B","G16B","G16B","G16H","G01N"],"num_claims":72,"abstract":"A method and system for predicting in advance of treatment whether a cancer patient is likely, or not likely, to obtain benefit from administration of a yeast-based immune response generating therapy, which may be yeast-based immunotherapy for mutated Ras-based cancer, alone or in combination with another anti-cancer therapy. The method uses mass spectrometry of a blood-derived patient sample and a computer configured as a classifier using a training set of class-labeled spectra from other cancer patients that either benefitted or did not benefit from an immune response generating therapy alone or in combination with another anti-cancer therapy. Also disclosed are methods of treatment of a cancer patient, comprising administering a yeast-based immune response generating therapy, which may be yeast-based immunotherapy for mutated Ras-based cancer, to a patient selected by a test in accordance with predictive mass spectral methods disclosed herein, in which the class label for the spectra indicates the patient is likely to benefit from the yeast-based immunotherapy."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies","description":"A method and system for predicting in advance of treatment whether a cancer patient is likely, or not likely, to obtain benefit from administration of a yeast-based immune response generating therapy,","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9653272","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9653272","citation_suggestion":"Patentable. \"Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies\" (US-9653272). https://patentable.app/patents/US-9653272","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9653272","json":"https://patentable.app/api/llm-context/US-9653272","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T16:52:10.027Z"}